Spiro-azacyclic derivatives and their use as therapeutic agents

Details Spiro-azacyclic derivatives and their use as therapeutic agents Spiro-azacyclic derivatives and their use as therapeutic agents

C - Chemistry, Metallurgy

07

D

C07D 491/10 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2287436

Substituted spiro-azacyclic derivatives of structural formula (I) are tachykinin receptor antagonists of use, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.

L'invention concerne des dérivés spiro-azacyliques substitués de la formule développée (I) constituant des antagonistes de récepteur de tachykinine s'utilisant, par exemple, dans le traitement ou la prévention de douleurs, d'inflammations, de migraines, de vomissements et d'algies post-zostériennes.

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