Spiro-azacyclic derivatives and their use as therapeutic agents

Details Spiro-azacyclic derivatives and their use as therapeutic agents Spiro-azacyclic derivatives and their use as therapeutic agents

C - Chemistry, Metallurgy

07

D

C07D 491/10 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2289037

Substituted spiro-azacyclic derivatives of structural formula (I) are tachykinin receptor antagonists of use, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.

Dérivés substitués spiro-azacycliques représentés par la formule (I) et qui sont des antagonistes du récepteur de tachykinine utiles, par exemple, pour le traitement et la prophylaxie de la douleur, de l'inflammation, de la migraine, du vomissement et de l'algie post-zostérienne.

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