Spiro[benzofurancycloalkane]carboxamides as 5ht3 antagonists

Details Spiro[benzofurancycloalkane]carboxamides as 5ht3 antagonists Spiro[benzofurancycloalkane]carboxamides as 5ht3 antagonists

C - Chemistry, Metallurgy

07

D

C07D 453/02 (2006.01) A61K 31/435 (2006.01) A61K 31/535 (2006.01) C07D 405/12 (2006.01) C07D 451/14 (2006.01) C07D 471/08 (2006.01) C07D 498/08 (2006.01)

Patent

CA 2081011

2081011 9116888 PCTABS00008 This invention is directed toward certain spiro[benzofuran-2(3H),1'-cycloalkane]carboxamides and their use as 5HT3-antagonists having unique central nervous system, anti-emetic and gastric prokinetic activity void of any significant D2-receptor binding properties. This invention also discloses novel processes necessary for their preparation.

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