C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 285/14 (2006.01) A61K 31/433 (2006.01) A61P 35/00 (2006.01) C07D 515/10 (2006.01) C07D 515/20 (2006.01)
Patent
CA 2702922
The present invention relates to compounds of Formula (I), below, (wherein X, R1, R2, R3, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity. Formula I [Chemical formula should be inserted here as it appears on abstract in paper form.]
La présente invention concerne des composés de formule (I), ci-dessous, (X, R1, R2, R3, p, E, le cycle A, et le cycle B étant tels que définis ici). La présente invention concerne également des compositions (y compris des composition pharmaceutiquement acceptables) comprenant ces composés, seuls ou en association avec un ou des agents thérapeutiques supplémentaires, et des procédés pour leur utilisation dans l'inhibition de l'activité de la kinésine KSP, et dans le traitement de maladies à prolifération cellulaire ou de troubles associés à l'activité de la kinésine KSP. Formule I [La formule chimique devrait être insérée ici comme elle apparaît sur l'abrégé sous forme papier].
Angeles Angie R.
Dai Chaoyang
Mansoor Umar Faruk
Siddiqui M. Arshad
Vitharana Lalalnthi Dilrukshi
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
LandOfFree
Spiro-condensed 1, 3, 4-thiadiazole derivatives for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Spiro-condensed 1, 3, 4-thiadiazole derivatives for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Spiro-condensed 1, 3, 4-thiadiazole derivatives for... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1715252