C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/06 (2006.01) A61K 31/445 (2006.01) A61K 38/04 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 471/10 (2006.01) C07D 491/10 (2006.01) C07D 495/10 (2006.01) C07K 5/02 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2110672
TITLE OF THE INVENTION SPIRO PIPERIDINES AND HOMOLOGS PROMOTE RELEASE OF GROWTH HORMONE ABSTRACT OF THE DISCLOSURE There are disclosed certain novel compounds identified as spiro piperidines and homologs which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to treat physiological or medical conditions characterized by a deficiency in growth hormone secretion, such as short stature in growth hormone deficient children, and to treat medical conditions which are improved by the anabolic effects of growth hormone. Growth hormone releasing compositions containing such spiro compounds as the active ingredient thereof are also disclosed.
Chen Meng-Hsin
Johnston David B. R.
Nargund Ravi P.
Patchett Arthur A.
Tata James R.
Merck & Co. Inc.
Swabey Ogilvy Renault
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