Spiro [piperidine-4,4'-thieno[3,2-c]pyran] derivatives and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 495/20 (2006.01) A61K 31/438 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2690249

The present invention relates to compounds having pharmacological activity towards the sigma (.sigma.) receptor, and more particularly to some thieno-pyrano-pyrazole derivatives, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and prophylaxis, in particular for the treatment of psychosis or pain.

La présente invention concerne des composés ayant une activité pharmacologique vis-à-vis du récepteur sigma (s), et plus particulièrement quelques dérivés de thiéno-pyrano-pyrazole, des procédés de préparation de ces composés, des compositions pharmaceutiques les comprenant, et leur utilisation en thérapie et en prophylaxie, en particulier pour le traitement de la psychose ou de la douleur.

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