Spiro-piperidine derivatives and their use as therapeutic...

Details Spiro-piperidine derivatives and their use as therapeutic... Spiro-piperidine derivatives and their use as therapeutic...

C - Chemistry, Metallurgy

07

D

C07D 491/107 (2006.01) A61K 31/395 (2006.01) A61K 31/435 (2006.01) A61K 31/438 (2006.01) A61K 31/445 (2006.01) A61K 31/451 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) A61K 31/54 (2006.01) A61K 31/675 (2006.01) C07D 211/56 (2006.01) C07D 491/10 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2257964

Substituted spiro-piperidine derivatives of structural formula (I) are tachykinin receptor antagonists of use, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.

Dérivés spiro-pipéridine substitués définis par la formule développée (1), antagonistes du récepteur de tachykinine, pouvant être utilisés par exemple dans le traitement ou la prévention des douleurs, des inflammations, des migraines, des vomissements et des algies post-zosteriennes.

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