Spiro-pyrano-pyrazole derivatives

Details Spiro-pyrano-pyrazole derivatives Spiro-pyrano-pyrazole derivatives

C - Chemistry, Metallurgy

07

D

C07D 491/20 (2006.01) A61K 31/438 (2006.01) A61P 23/00 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2678134

The present invention relates to compounds of formula (I) having pharmacological activity towards the sigma (.sigma.) receptor, and more particularly to some spiro-pyrano-pyrazole derivatives, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and prophylaxis, in particular for the treatment of psychosis.

Cette invention concerne des composés représentés par la formule (I) ayant une activité pharmacologique vis-à-vis du récepteur sigma (.sigma.). Plus particulièrement, cette invention concerne certains dérivés de spiro-pyrano-pyrazole, des procédés permettant de préparer de tels composés, des compositions pharmaceutiques comprenant de tels composés, ainsi que leur utilisation à des fins thérapeutiques et prophylactiques, plus particulièrement pour traiter la psychose.

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