Spirocyclic cyclohexane derivatives

Details Spirocyclic cyclohexane derivatives Spirocyclic cyclohexane derivatives

C - Chemistry, Metallurgy

07

D

C07D 471/10 (2006.01) A61K 31/407 (2006.01) A61P 25/00 (2006.01) C07D 491/107 (2006.01) C07D 495/10 (2006.01)

Patent

CA 2679173

The present invention relates to spirocyclic cyclohexane derivatives of formula (I), methods for the production thereof, medicaments containing these compounds and the use of spirocyclic cyclohexane derivatives for producing medicaments. R1 and R2 form a pyrrolidine or an azetidine ring, which results in an increased metabolic stability.

L'invention concerne des dérivés de cyclohexane spirocycliques de formule (I), des procédés pour leur production, des médicaments contenant ces composés, ainsi que l'utilisation de dérivés de cyclohexane spirocycliques pour produire des médicaments. R1 et R2 forment un cycle pyrrolidine ou azétidine, ce qui entraîne une augmentation de la stabilité métabolique.

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