Spirocyclic gpr40 modulators

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 62/34 (2006.01) A61K 31/185 (2006.01) A61K 31/33 (2006.01) A61P 3/10 (2006.01) C07D 221/00 (2006.01) C07D 231/00 (2006.01) C07D 249/00 (2006.01) C07D 271/00 (2006.01) C07D 277/00 (2006.01) C07D 311/00 (2006.01)

Patent

CA 2739888

The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula IA, IB, I'A or I'B, where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.

Cette invention concerne des composés utilisés, notamment, pour traiter les désordres métaboliques chez un sujet. Ces composés sont de formule générale IA, IB, I'A ou I'B, la définition des variables étant donnée dans la description. Linvention concerne également des compositions contenant les composés, et des méthodes dutilisation de ces composés, dans la préparation de médicaments et le traitement de désordres métaboliques, par exemple le diabète de type II.

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