Spirocyclic ureas, compositions containing such compounds...

Details Spirocyclic ureas, compositions containing such compounds... Spirocyclic ureas, compositions containing such compounds...

C - Chemistry, Metallurgy

07

D

C07D 239/70 (2006.01) A61K 31/4168 (2006.01) A61K 31/537 (2006.01) A61P 3/08 (2006.01) C07D 233/76 (2006.01) C07D 401/04 (2006.01) C07D 487/10 (2006.01)

Patent

CA 2508581

The present invention relates to spirocyclic ureas, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.

L'invention concerne des urées spirocycliques, des compositions les contenant ainsi que des procédés de traitement. Les composés selon l'invention sont des antagonistes des récepteurs du glucagon et peuvent par conséquent servir à traiter un diabète sucré de type 2, le prévenir ou retarder son déclenchement.

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