Spiroindolinone derivative prodrugs

Details Spiroindolinone derivative prodrugs Spiroindolinone derivative prodrugs

C - Chemistry, Metallurgy

07

D

C07D 471/10 (2006.01) A61K 31/438 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2748957

There are provided compounds of the formula (I) and pharmaceutically acceptable salts and esters and enantiomers thereof, wherein X, Y, V, R1, R2 and R are as described herein. The compounds have utility as antiproliferative agents, especially, as anticancer agents.

La présente invention concerne des composés de formule (I) et des sels, des esters et des énantiomères de ceux-ci pharmaceutiquement acceptables, dans laquelle X, Y, V, R1, R2 et R sont tels que décrits ici. Les composés sont utiles comme agents anti-prolifératifs, en particulier, comme agents anti-cancéreux.

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