C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/10 (2006.01) A61K 31/438 (2006.01) A61P 3/04 (2006.01)
Patent
CA 2490531
The present invention discloses compounds according to formula which are novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
L'invention concerne des composés représentés par la formule (I) qui constituent de nouveaux antagonistes de l'hormone concentrant la mélanine (MCH), et des procédés de préparation de ces composés. Dans une autre forme de réalisation, l'invention concerne des compositions pharmaceutiques comprenant de tels antagonistes de MCH, et des procédés d'utilisation de celles-ci pour traiter l'obésité, des troubles métaboliques, des troubles de l'alimentation tels que l'hyperphagie, et le diabète.
Burnett Duane A.
Domalski Martin S.
Sasikumar Thavalakulam K.
Wu Wen-Lian
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
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