Spliceosomal protein and its use

Details Spliceosomal protein and its use Spliceosomal protein and its use

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2376055

The invention relates to a spliceosome protein that is associated with the U11/U12 snRNP complex of the U12-dependent spliceosome and that is specific of said spliceosome. Said protein and the DNA sequence encoding it are useful for the diagnostics of certain autoimmune diseases and of diseases that are caused by defects in the splicing apparatus.

La présente invention concerne une protéine d'épissosome associée au complexe U11/U12 snRNP de l'épissosome U12-dépendant et spécifique de cet épissosome. Cette protéine et la séquence d'ADN codant pour elle peuvent être utilisées pour diagnostiquer certaines maladies auto-immunes ou des maladies liées à une déficience du système d'épissage.

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