Spongiform encephalopathy detection methods

G - Physics – 01 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

G01N 33/68 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2205179

A method for detecting the presence of spongiform encephalopathy in an animal comprising determining the presence and/or amount of agent (e.g. by the use of 2DPAGE, followed by staining and densitometry readings of the stained agent) in a body fluid (e.g. cerebrospinal fluid) of test animal which cross-reacts with antibody raised against apoliprotein E, and has a molecular weight of between 34 and 38 kDa and a pI of between 5.4 and 5.7 comparing the concentration with a control value, and correlating the relationship between the two with the likely presence of spongiform encephalopathy in the animal.

Ce procédé de détection de la présence d'une encéphalopathie spongiforme, chez un animal, comprend les étapes consistant à déterminer la présence et/ou la quantité d'un agent (par exemple par électrophorèse bidimensionnelle sur gel polyacrylamide, suivie d'une coloration et de lectures densitométriques de l'agent coloré), dans un fluide organique (par exemple le fluide cérébro-spinal) de l'animal examiné, lequel agent réagit de façon croisée avec l'anticorps dirigé contre l'apoliprotéine E et possède un poids moléculaire compris entre 34 et 38 kDa ainsi qu'un pI compris entre 5,4 et 5,7, puis à comparer la concentration avec une valeur témoin, et enfin à déduire du rapport entre ces deux valeurs la présence probable chez l'animal de l'encéphalopathie spongiforme.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Spongiform encephalopathy detection methods does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Spongiform encephalopathy detection methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Spongiform encephalopathy detection methods will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1400372

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.