Spot-on formulations for combating parasites

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/415 (2006.01) A61K 31/365 (2006.01) A61K 31/7048 (2006.01) A61K 47/32 (2006.01) A61P 33/00 (2006.01)

Patent

CA 2608788

In particular this invention provides for spot-on compositions for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: (1) a composition comprising (A) an effective amount of a 1- .rho.henylpyrazole derivative; and (B) an effective amount of emamectin, latidectin or lepimectin; (2) an acceptable liquid carrier vehicle; and (3) optionally, a crystallization inhibitor. The invention also provides for a method of treating parasitic infestations or for the prophylaxis of parasite infestations in mammals or birds which comprises topically applying to said mammal treating parasitic infestations or for the prophylaxis of parasite infestations in mammals or birds which comprises topically applying to said mammal or bird an effective amount of a composition according to the present invention.

L'invention concerne, en particulier des compositions de traitement cutané localisé permettant de traiter et de prévenir les infestations parasitaires chez les mammifères ou les oiseaux, qui comprennent: 1) une composition renfermant A) une quantité efficace d'un dérivé de 1-?hénylpyrazole, et B) une quantité efficace d'émamectine, de latidectine ou de lépimectine; 2) un excipient liquide acceptable; et (3) éventuellement, un inhibiteur de cristallisation. L'invention concerne également une méthode permettant de traiter et de prévenir les infestations parasitaires chez les mammifères ou des oiseau, qui consiste à leur appliquer de manière topique une quantité efficace de la composition de l'invention.

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