A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 39/395 (2006.01)
Patent
CA 2564324
The invention relates to spray-dried powders and to methods for producing the same. The inventive powders comprise a pharmaceutically active ingredient and one or more 1,4 O-linked saccharose derivatives selected from the compounds: 1,4 O-linked D-Gal saccharose (lactosucrose), 1,4 O-linked D-Glu saccharose (glucosyl sucrose), or 1,4 O-linked Glu-Glu saccharose (maltosyl sucrose). Preferred combinations contain glucosyl or maltosyl sucrose.
L'invention concerne des poudres séchées par pulvérisation et des procédés pour les réaliser. Les poudres de la présente invention contiennent un agent pharmaceutique et un ou plusieurs dérivés de saccharose à liaison O en 1,4, sélectionnés parmi les composés suivants: saccharose D-Gal à liaison O en 1,4 (lactosucrose), saccharose D-Glu à liaison O en 1,4 (glucosyle sucrose), saccharose Glu-Glu à liaison O en 1,4 (maltosyle sucrose). Des compositions préférées comportent du glucosyle sucrose et du maltosyle sucrose.
Bassarab Stefan
Bechtold-Peters Karoline
Friess Wolfgang
Fuhrherr Richard
Garidel Patrick
Boehringer Ingelheim Pharma Gmbh & Co.kg
Fetherstonhaugh & Co.
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