Stabilised compositions

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/195 (2006.01) A61K 39/02 (2006.01) A61K 39/39 (2006.01) C07K 14/245 (2006.01) G01N 33/483 (2006.01)

Patent

CA 2542777

This invention relates to the stabilization of a bacterial ADP-ribosylating exotoxin class protein (bARE), a method for analysing a bARE class protein, a method for the stabilization of the bARE class bacterial protein, compositions comprising a stabilized bARE protein, compositions comprising a substantially integral bARE class protein and immunogenic composition formulations incorporating same.

L'invention concerne la stabilisation d'une protéine de classe exotoxine ADP-ribosylante bactérienne, un procédé pour analyser une protéine de classe exotoxine ADP-ribosylante bactérienne, un procédé pour stabiliser la protéine de classe exotoxine ADP-ribosylante bactérienne, des compositions comprenant une protéine de classe exotoxine ADP-ribosylante bactérienne stabilisée, des compositions comprenant une protéine de classe exotoxine ADP-ribosylante bactérienne pratiquement intégrale, ainsi que des formulations de compositions immunogènes renfermant cette dernière.

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