Stabilised mrna tumour vaccine

Details Stabilised mrna tumour vaccine Stabilised mrna tumour vaccine

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 38/19 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2473135

The invention relates to a pharmaceutical composition comprising at least one mRNA, which contains at least one region that codes for an antigen from a tumour, combined with an aqueous solvent and preferably with a cytokine, e.g. GM-CSF. The invention also relates to a method for producing the pharmaceutical composition. The inventive pharmaceutical composition is used in particular for the treatment and/or prophylaxis of cancer.

L'invention concerne une composition pharmaceutique contenant au moins un ARNm et comprenant au moins une zone codant pour au moins un antigène provenant d'une tumeur, en association avec un solvant aqueux, de préférence une cytokine, par ex. le GM-CSF. La présente invention porte également sur un procédé pour préparer cette composition pharmaceutique, laquelle est destinée notamment au traitement thérapeutique et/ou prophylactique du cancer.

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