Stabiliser for radiopharmaceuticals

Details Stabiliser for radiopharmaceuticals Stabiliser for radiopharmaceuticals

A - Human Necessities

61

K

A61K 51/12 (2006.01) A61K 47/06 (2006.01) A61K 51/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2411577

The present invention provides an improved stabiliser for radiopharmaceuticals which inhibits impurities from being produced by two kinds of decomposition mechanisms and exhibits such an effect that the shelf life of a radiopharmaceutical after its preparation is prolonged as compared with conventional ones. The improvement comprises a combination of an amino- substituted aromatic carboxylic acid or its salt, ester or amide in combination with a diphosphonic acid or its salt.

L'invention concerne un agent stabilisant amélioré pour produits radiopharmaceutiques, capable d'inhiber des impuretés produites par deux types de mécanismes de décomposition et de présenter un effet tel que la durée de conservation d'un produit radiopharmaceutique après sa préparation soit prolongée comparativement aux produits conventionnels. Le produit amélioré selon l'invention est caractérisé en ce qu'il comprend une combinaison d'un acide carboxylique aromatique portant un substituant amino, ou de son sel, ester ou amide, avec un acide diphosphonique ou un sel de celui-ci.

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