A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 2/07 (2006.01) A23J 7/00 (2006.01) A23L 3/02 (2006.01) A61K 9/127 (2006.01) A61K 31/20 (2006.01) A61K 31/66 (2006.01) A61L 2/00 (2006.01)
Patent
CA 2443362
A method for sterilizing a lipid-containing formulation wherein the pH and the ionic strength of the lipid-containing formulation are optionally adjusted and the lipid-containing formulation is subjected to a temperature of between about 126 degrees celcius and about 130 degrees celcius for a time of between about 2 minutes and about 10 minutes. A stabilizing excipient is optionally added to the lipid-containing formulation.
La présente invention concerne un procédé de stérilisation d'une formulation contenant des lipides selon lequel on ajuste facultativement le pH et la force ionique de la formulation contenant des lipides et on soumet cette dernière à une température comprise entre environ 126 ·C et environ 130 ·C pendant une durée comprise entre environ 2 minutes et environ 10 minutes. On ajoute facultativement un excipient stabilisateur à la formulation contenant des lipides.
Diluzio Willow R.
Hui Poh K.
Bristol-Myers Squibb Pharma Company
Gowling Lafleur Henderson Llp
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