Stabilization of amorphous drugs using sponge-like carrier...

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A61K 31/41 (2006.01) A61K 31/496 (2006.01)

Patent

CA 2728979

The present invention relates to drug formulations for the stabilization of amorphous forms of drugs. In particular the present invention relates to pharmaceutical compositions comprising sponge- like carrier matrices, particularly polyelectrolyte complexes or porous particles. The invention also relates to methods for the production of such pharmaceutical compositions.

La présente invention concerne des formulations de médicaments pour la stabilisation des formes amorphes de médicaments. En particulier, la présente invention concerne des compositions pharmaceutiques qui comprennent des matrices de support de type éponge, plus particulièrement des complexes polyélectrolytes ou des particules poreuses. Linvention concerne également des procédés de production de telles compositions pharmaceutiques.

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