A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/502 (2006.01) A61K 31/00 (2006.01) A61K 31/17 (2006.01) A61K 31/4353 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/4745 (2006.01) A61K 31/50 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/505 (2006.01) C12Q 1/00 (2006.01)
Patent
CA 2467689
The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.
La présente invention concerne des méthodes permettant de stabiliser la sous-unité alpha du facteur inductible par hypoxie (HIF). Cette invention a également trait à des méthodes de prévention, de prétraitement ou de traitement de troubles liés audit facteur, notamment des troubles ischémiques et hypoxiques. Cette invention a également trait à des composés utilisés dans ces méthodes.
Arend Michael P.
Flippin Lee A.
Guenzler-Pukall Volkmar
Neff Thomas B.
Wang Qingjian
Fibrogen Inc.
Gowling Lafleur Henderson Llp
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