Stabilization of immunogens derived from paramyxoviruses

Details Stabilization of immunogens derived from paramyxoviruses Stabilization of immunogens derived from paramyxoviruses

A - Human Necessities

61

K

A61K 39/155 (2006.01) A61K 39/39 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2432423

Subunit non-adjuvanted immunogenic compositions of respiratory syncytial virus were stabilized by the formulation with various stabilizing agents including monosodium glutamate. The formulations retained protein conformation for at least 8 weeks at elevated temperatures.

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