C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/68 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C12N 9/16 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2496146
The present invention is directed at stabilizing linear polynucleotides against exonucleolytic attack. Adding to both ends of a double-stranded linear DNA a target sequence for a DNA-binding protein the double-stranded linear DNA with the two added target sequences has an increased stability against exonucleolytic attack when contacted with the DNA-binding protein.
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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