C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/88 (2006.01) A61K 9/12 (2006.01) A61K 9/127 (2006.01) A61K 47/24 (2006.01) A61K 47/28 (2006.01) A61K 48/00 (2006.01) C12N 15/00 (2006.01) C12N 15/10 (2006.01)
Patent
CA 2315708
The present invention provides a lipsomal aerosol composition, comprising a pharmaceutical compound, a cationic lipid, (c) a neutral co-lipid; and (d) tryptone. Also provided is a nebulized cationic lipid:DNA suspension useful for lipid-DNA transfections, wherein said cationic lipid is bis(guanidinium)- tren-cholesterol.
La présente invention concerne une composition liposomique en aérosol, refermant un composé pharmaceutique, un lipide cationique, c) un co-lipide neutre, et d) de la tryptone. L'invention concerne également une suspension nébulisée lipide cationique:ADN, utile pour des transfections lipides-ADN dans lesquelles du bis(guanidium)-tren-cholestérol constitue ledit lipide cationique.
Densmore Charles L.
Kinsey Berma M.
Knight J. Vernon
Waldrep J. Clifford
Borden Ladner Gervais Llp
Research Development Foundation
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