Stabilization of pleuromutilin derivatives against oxidation...

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A61K 31/22 (2006.01) A23K 1/16 (2006.01) A61K 31/215 (2006.01)

Patent

CA 1173752

GC157 Abstract STABILIZATION OF PLEUROMUTILIN DERIVATIVES AGAINST OXIDATION BY SODIUM HYPOCHLORITE IN AQUEOUS SOLUTION A composition is provided which comprises a hypochlorite scavenger and a compound of the formula Image wherein R1 is either ethyl or vinyl, n is an integer from 2 to 5 and each of R2 and R3 is an alkyl of 1 to 10 carbon atoms, and pharmaceutically acceptable salts of said compound. Such composition is use- ful in treating water having hypochlorite present when such water is prepared as drinking water for farm animals to serve as a pharmacologically active treatment.

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