Stabilized, aqueous, film-forming antimicrobial compositions...

A - Human Necessities – 61 – K

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A61K 33/40 (2006.01) A01N 59/00 (2006.01) A61K 8/22 (2006.01) A61K 8/81 (2006.01) A61K 47/32 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2107780

2107780 9219230 PCTABS00017 What is provided herein is a stabilized, aqueous, film-forming, antimicrobial composition of hydrogen peroxide. The active, oxygen-generating hydrogen peroxide component in the composition is stabilized in an aqueous-polyol solvent system of predetermined polarity containing PVP. In contrast, similar formulations without PVP experienced a loss of peroxide activity upon standing. Suitably, the composition herein includes about 1-20 % by weight hydrogen peroxide, about 0.1-50 % by weight PVP, and about 0.1-80 % by weight of a polyol, the rest being water. Preferably, about 5-20 % by weight of water is present in the composition. Additional solvents may be included therein, such as alcohols, ether oxides, esters, triglycerides of fatty acids, hydrocarbons, N-vinyl lactams, silicone oils, and polyether oligomers.

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