Stabilized ascorbic acid solutions; use thereof; process for...

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A61K 31/375 (2006.01) A61K 8/34 (2006.01) A61K 8/67 (2006.01) A61Q 17/04 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2396927

This invention relates to improved solutions comprising ascorbic acid (vitamin C). These solutions may comprise as much as 15% ascorbic acid; they are stable for at least two years, without no significant development of yellowish coloration and no substantial (not more than 10%) degradation of the vitamin. The process involves sequential additions of ascorbic acid and ethoxydiglycol to a first solution of vitamin in water, which are followed by addition of propylene glycol and fragrances. The high stirring speed that occurs during the additions favorises a process of micronisation. Mild heating is used to achieve ascorbic acid concentrations equivalent to about 6% in 10% water or higher.

La présente invention concerne des solutions améliorées, comprenant de l'acide ascorbique (vitamine C). Ces solutions peuvent comprendre jusqu'à 15 % d'acide ascorbique et sont stables pendant au moins deux ans, sans apparition d'une coloration jaunâtre et sans dégradation sensible (pas plus de 10%) de la vitamine. Leur procédé de production consiste à ajouter plusieurs fois, de manière séquentielle, de l'acide ascorbique et de l'éthoxydiglycol à une première solution de vitamine dans de l'eau, puis à ajouter du propylène glycol et des parfums. La haute vitesse d'agitation qui intervient lors des ajouts favorise un processus de micronisation. Un chauffage doux est utilisé afin d'obtenir des concentrations en acide ascorbique équivalentes à environ 6 % dans au moins 10 % d'eau.

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