Stabilized controlled release formulations having acrylic...

Details Stabilized controlled release formulations having acrylic... Stabilized controlled release formulations having acrylic...

A - Human Necessities

61

K

A61K 9/32 (2006.01) A61K 9/28 (2006.01) A61K 9/50 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2074309

A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of an acrylic polymer is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of the plasticized acrylic polymer and then curing the coated substrate at a temperature above the glass transition temperature of the plasticized acrylic polymer, until the coated dosage form attains a stabilized dissolution profile substantially unaffected by exposure to storage conditions of elevated temperature and/or elevated relative humidity.

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