C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/62 (2006.01) A61K 8/67 (2006.01) A61K 31/375 (2006.01) A61P 3/02 (2006.01) A61P 35/00 (2006.01) A61Q 19/00 (2006.01)
Patent
CA 2523042
Ascorbic acid derivatives of the general formula I: wherein R1 is a C2-C22 acyl group, an amino acid group, or a C1-C17 alkyl group; R2 is ammonium or a metal cation; and each of R3 or R4, independently, is hydrogen, a C2-C22 acyl group, an amino acid residue, or a C1-C17 alkyl group, are more stable than ascorbic acid and can be used as a source of vitamin C in pharmaceutical, nutraceutical and cosmetic compositions.
L'invention concerne des dérivés d'acide ascorbique de formule générale (I), dans laquelle R?1¿ est un groupe acyle C¿2?-C¿22?, un groupe d'acides aminés, ou un groupe alkyle C¿1?-C¿17?; R?2¿ représente ammonium ou un cation métallique; et R?3¿ ou R?4¿, représente indépendamment hydrogène, un groupe acyle C¿2?-C¿22?, un résidu d'acide aminé, ou un groupe alkyle C¿1?-C¿17?. Lesdits dérivés sont plus stables que de l'acide ascorbique et peuvent être utilisés en tant que source de vitamine C dans des compositions pharmaceutiques, nutraceutiques et cosmétiques.
Babtsov Vladimir
Belakhov Valery
Kvitnitsky Emma
Shapiro Yury
Borden Ladner Gervais Llp
Tagra Biotechnologies Ltd.
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