A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/404 (2006.01) A61K 9/20 (2006.01) A61K 47/34 (2006.01) A61K 47/40 (2006.01) A61P 3/06 (2006.01)
Patent
CA 2615941
The present invention is a new stable extended release drug composition particularly suitable for use as an antihypercholesterolaemic or antihyperlipidaemic agent. The present invention is specifically a drug composition comprising a pharmaceutical, a complexing agent and a matrix- forming agent, and a method for manufacturing same. When applied to acid- labile drugs like HMG-CoA reductase inhibitors, the resulting drug composition is stabilized and is characterized by an extended-release profile.
La présente invention concerne une nouvelle composition médicamenteuse à libération prolongée, stable, particulièrement appropriée pour être utilisée en tant qu'agent antihypercholestérolémique ou antihyperlipidémique. La présente invention concerne spécifiquement une composition médicamenteuse comprenant un agent pharmaceutique, un agent complexant et un agent de formation de matrice, ainsi qu'un procédé de fabrication de ladite composition. Lorsqu'appliquée sur des médicaments labiles en milieu acide tels que des inhibiteurs de la HMG-CoA réductase, la composition médicamenteuse obtenue est stabilisée et est caractérisée par un profil de libération prolongée.
Bergstein Corey
Orbus Pharma Inc.
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