A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4535 (2006.01) A61K 47/18 (2006.01) A61K 47/20 (2006.01) A61P 19/10 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2408563
The present invention is directed to pharmaceutical formulations containing 6- hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4- methoxyphenyl)benzo[b]thiophene or a salt thereof; stabilized to oxidation or other forms of decomposition by incorporation of a stabilizing agent selected from methionine, acetylcysteine, cysteine or salts thereof.
L'invention concerne des formulations pharmaceutiques contenant du 6-hydroxy-3-(4-[2-(pipéridin-1-yl)éthoxy]phénoxy)-2-(4-méthoxyphényl)benzo[b]thiophène ou un sel de celui-ci. Ces formulations sont stabilisées afin de résister à l'oxydation et à d'autres formes de décomposition par l'incorporation d'un agent stabilisateur choisi parmi les composés suivants : méthionine, acétylcystéine, cystéine ou des sels de ceux-ci.
Bashore Fadia Najjar
Hartauer Kerry John
Minnett Michael Dean
Rickard Eugene Clark
Tingle Cheryl Ann
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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