A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/10 (2006.01) A61K 9/00 (2006.01) A61K 35/76 (2006.01) A61K 39/235 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2469721
A method is disclosed to stabilize compositions comprizing airborne viruses, particularly Adenoviruses, and more particularly recombinant Adenoviruses, by adding to the compositions a non-ionic detergent which comprises an alkyl moiety and polyethylene glycol (PEG). Pharmaceutical and other compositions of Adenoviruses, particularly recombinant Adenoviruses suitable for methods of gene therapy, which comprise such detergents are also disclosed.
L'invention concerne une méthode permettant de stabiliser des compositions comprenant des virus de l'air, notamment des adénovirus, et plus particulièrement des adénovirus de recombinaison. Ladite méthode consiste à ajouter un détergent non ionique aux compositions, ce détergent comprenant une fraction alkyle et un polyéthylène glycol (PEG). L'invention concerne également des compositions pharmaceutiques et d'autres compositions d'adénovirus, en particulier, des adénovirus de recombinaison appropriés pour être utilisés dans des méthodes de thérapie génique comprenant les détergents précités.
Lehmberg Elisabeth
Pungor Erno
Marks & Clerk
Schering Aktiengesellschaft
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