Stabilized formulations of alpha adrenergic receptor...

A - Human Necessities – 61 – K

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A61K 31/505 (2006.01) A01N 25/00 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/165 (2006.01) A61K 31/24 (2006.01) A61K 31/415 (2006.01) A61K 31/417 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 38/46 (2006.01) A61K 47/12 (2006.01) A61K 47/16 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2489526

The present invention provides compositions and stable liquid formulations comprising alpha adrenergic receptor antagonists and use therof for increasing blood flow. In one embodiment, the stable liquid formulations of this invention are useful for reversing the effects of an anesthetic agent, preferably a long-lasting local anesthetic agent administered in conjunction with an alpha adrenergic receptor agonist.

La présente invention concerne des compositions et des formulations liquides stables comprenant des antagonistes de récepteurs adrénergiques alpha et leur utilisation pour augmenter l'afflux sanguin. Dans un mode de réalisation, les formulations liquides stables de l'invention sont utiles pour inverser les effets d'un agent anesthésique, de préférence d'un agent anesthésique local administré conjointement avec un agoniste de récepteurs adrénergiques alpha.

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