Stabilized human papillomavirus formulations

Details Stabilized human papillomavirus formulations Stabilized human papillomavirus formulations

A - Human Necessities

61

K

A61K 39/12 (2006.01) C07K 14/025 (2006.01) C12N 7/04 (2006.01)

Patent

CA 2286294

Human papillomavirus (HPV) antigen formulations are disclosed which prevent protein aggregation and show prolonged stability as aqueous solutions. These formulations comprise a salt (such as sodium chloride) and a non ionic surfactant (Polysorbate 80 such as Tween 80) in physiologically acceptable concentrations.

L'invention concerne des formulations d'antigène du virus du papillome humain (HPV), qui empêchent l'agrégation des protéines et présentent une stabilité prolongée sous forme de solutions aqueuses. Lesdites formulations comprennent un sel (par exemple, chlorure de sodium) et un tensioactif non ionique (Polysorbate 80, à savoir par exemple Tween 80??¿) en concentrations physiologiquement acceptables.

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