Stabilized injectable solutions of piroxicam

A - Human Necessities – 61 – K

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A61K 31/54 (2006.01) A61K 47/00 (2006.01) A61K 47/26 (2006.01)

Patent

CA 1251734

STABILIZED INJECTABLE SOLUTIONS OF PIROXICAM Abstract Stable aqueous solutions of piroxicam suitable for pharmaceutical use are disclosed. These solutions all contain piroxicam in conjunction with a sub-stoichio- metric amount of D-(-)-N-methylglucamine and have propylene glycol, ethanol and water as the solvent, with the pH of said solutions being in the range of from about pH 8 to about pH 9. These particular pharmaceutical compositions possess excellent chemical stability properties and are especially suitable for parenteral administration.

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