Stabilized insulin-like growth factor polypeptides

A - Human Necessities – 61 – K

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Details

A61K 38/30 (2006.01) C07K 14/65 (2006.01)

Patent

CA 2653781

The invention relates to stabilized polypeptides having an IGF-I or IGF-2 sequence and an E-peptide sequence, where the natural physiological cleavage of the E-peptide from the IGF is prevented.

L'invention concerne des polypeptides stabilisés comportant une séquence IGF-I ou IGF-2 et une séquence peptidique E et dont le clivage physiologique naturel du peptide E des séquences IGF est évité.

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