Stabilized nucleic acid compositions and methods of...

A - Human Necessities – 61 – K

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A61K 9/14 (2006.01) A61K 9/10 (2006.01) A61K 9/19 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2349859

Preparations of nucleic acid condensates and compositions containing such condensates are provided. The nucleic acid condensates are in the form of small particles that are stable when subjected to destabilizing conditions such as lyophilizing, freeze-thawing, and prolonged liquid storage. These compositions may be used to deliver nucleic acid to cells.

L'invention concerne des préparations de condensats d'acides nucléiques et des compositions les contenant. Les condensats d'acides nucléiques se présentent sous forme de petites particules qui sont stables quand elles sont soumises à des conditions déstabilisantes telles que lyophilisation, congélation/décongélation et conservation prolongée en milieu liquide. Ces compositions peuvent être utilisées pour apporter des acides nucléiques à des cellules.

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