Stabilized pharmaceutical compositions and methods for...

A - Human Necessities – 61 – K

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A61K 47/02 (2006.01) A61K 9/00 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2158140

A stabilised pharmaceutical composition containing one or more macromolecules selected from nucleic acids, lipids and carbohydrates, and/or one or more macromolecular complexes. The composition is characterized in that it includes one or more pharmaceutically acceptable carriers of which at least one contains heavy water (D2O). The composition is suitable for preparing vaccines.

L'invention concerne une composition pharmaceutique stabilisée comprenant une ou plusieurs macromolécule(s) choisie(s) parmi les acides nucléiques, les lipides ou les glucides, et/ou un ou plusieurs complexe(s) macromoléculaire(s), caractérisée en ce qu'elle comprend un ou plusieurs véhicule(s) pharmaceutiquement acceptable(s), l'un au moins de ces véhicules contenant de l'eau lourde (D2O). Application à la préparation de vaccins.

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