A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/724 (2006.01) A61K 9/48 (2006.01) A61K 31/404 (2006.01) A61P 3/06 (2006.01)
Patent
CA 2604861
The present invention relates to pharmaceutical compositions containing an HMG- CoA reductase inhibitor which is protected from destabilization in acidic environments by utilizing cyclodextrin as an inclusion complexing agent. The present invention further relates to the preparation of inclusion complexes of HMG-CoA and cyclodextrin and to their use in the treatment of hypercholesterolemia and hyperlipidemia.
La présente invention concerne des compositions pharmaceutiques contenant un inhibiteur de la HMG-CoA réductase qui est protégé d'une déstabilisation dans les environnements acides au moyen de l'utilisation de la cyclodextrine comme agent complexant d'inclusion. La présente invention concerne de plus la préparation de complexes d'inclusion de HMG-CoA et de cyclodextrine et leur utilisation dans le traitement de l'hypercholestérolémie et de l'hyperlipidémie.
Bergstein Corey
Orbus Pharma Inc.
LandOfFree
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