A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/59 (2006.01) A61K 9/20 (2006.01) A61K 47/10 (2006.01) A61K 47/44 (2006.01)
Patent
CA 2106423
A solid pharmaceutical composition consisting of the following ingredients (a), (b), (c) and (d), namely: (a) at least one active component selected from pharmaceutically active derivatives of vitamin D2 and vitamin D3; (b) at least one pharmaceutically acceptable antioxidant selected from butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), vitamin E, propyl gallate, .beta.-carotene and ascorbic acid; (c) at least one pharmaceutically acceptable polyoxyalkyl stabilizer; and (d) at least one solid pharmaceutical excipient or carrier selected from lactose, sorbitol and calcium phosphate, in an amount sufficient to impart the characteristics of a solid to the composition. It is provided that ingredients (b) and (c) are present in amounts which together are effective to stabilize ingredient (a).
Gowling Lafleur Henderson Llp
Silver David Isaac
Teva Pharmaceutical Industries Ltd.
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