Stabilized protein or peptide conjugates

Details Stabilized protein or peptide conjugates Stabilized protein or peptide conjugates

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/16 (2006.01) A61K 47/48 (2006.01) C07K 14/31 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2064689

A process for extending the half-life in vivo by a biologically active protein or peptide, characterized by covalently coupling said protein or peptide to a polypeptide fragment capable of binding to a serum protein, whereby when administering the result- ing protein or peptide congugate its binding to the serum protein results in extended biological activity; the use of the protein or peptide conjugate above for manufacturing a medicament which, when administered to a mammal including man, shows ex- tended half-life in vivo; and a method of therapeutic or prophylactic treatment.

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