Stabilized pvp-i solutions

Details Stabilized pvp-i solutions Stabilized pvp-i solutions

A - Human Necessities

61

K

A61K 33/18 (2006.01) A01N 59/12 (2006.01) A61K 9/00 (2006.01) A61K 31/79 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2062001

Povidone-Iodine (PVP-I) solutions stable according to U.S.P. standards and a method for preparing the same are disclosed. The PVP-I solution includes a microbicidal effective amount of available iodine and an alkalinizing agent in an effective amount to maintain the stability of the solution according to U.S.P. standards when said solution is stored in a glass container, the solution being non-buffered. In preferred embodiments, the iodophor solution is a microbicidal PVP-I solution for ophthalmic use.

Divulgation de solutions de povidone-iode (PVP-I) stables d'après les normes USP et d'une méthode pour les préparer. La solution de PVP-I comprend une quantité d'iode disponible suffisante pour exercer un effet microbicide et une quantité suffisante d'un agent alcalinisant pour garder la solution stable d'après les normes USP lorsque la solution en question est conservée dans un contenant de verre, la solution n'étant pas tamponnée. Dans les versions préférées, la solution d'iodophore est une solution de PVP-I microbicide pour usage ophtalmique.

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