Stabilized radiopharmaceutical compositions

Details Stabilized radiopharmaceutical compositions Stabilized radiopharmaceutical compositions

C - Chemistry, Metallurgy

07

K

530/7.1

C07K 14/58 (2006.01) A61K 51/08 (2006.01)

Patent

CA 2019035

Derivatives of synthetic fragments of mammalian atrial natriuretic factor (ANF) in which a chelate molecule is attached to the N-terminal of the peptide are described. The chelate component allows the facile labelling of these peptides with metallic isotopes such as Tc-99m, Ga-67, In-111 and others. These radioactive chelates are useful in determining the in vivo behavior and fate of derivatives of ANF.

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