Stabilized solid dispersions of misoprostol

A - Human Necessities – 61 – K

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Details

A61K 31/557 (2006.01) A61K 9/10 (2006.01) A61K 9/14 (2006.01) A61K 31/5575 (2006.01)

Patent

CA 2222811

Stable solid state amorphous dispersions of misoprostol are disclosed which are prepared using the ethanol solvent method, lyophilization and spray drying techniques, such dispersions have utility in a wide variety of formulations for the delivery of misoprostol through various routes.

Dispersions stables, solides, amorphes de misoprostol, préparées par le procédé à solvant éthanol, par lyophilisation ou par séchage par pulvérisation. Ces dispersions sont utiles dans une grande variété de préparations pour l'administration de misoprostol par différentes voies.

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