Stabilized solid dosage forms of choline metal...

Details Stabilized solid dosage forms of choline metal... Stabilized solid dosage forms of choline metal...

A - Human Necessities

61

K

A61K 47/38 (2006.01) A61K 9/20 (2006.01) A61K 31/615 (1995.01)

Patent

CA 2071262

The stability of compositions of choline salicylate-metal salicylate-carboxymethylcellulose is improved by the incorporation therein of microcrystalline cellulose. The microcrystalline cellulose is linked to the remainder of the composition by liquid bridges and is preferably present in an amount of about 2.5-25% by weight. The microcrystalline cellulose enhances the stability of the composition and thereby enhances solid dosage forms thereof such as tablets, capsules, suppositories and granules.

Amélioration de la stabilité de compositions de choline-salicylate - salicylate métallique - carboxyméthylcellulose grâce à l'incorporation de cellulose microcristallisée. Celle-ci est liée au reste de la composition par des ponts liquides; la composition en renferme de préférence environ 2,5 à 25 % en poids. La cellulose microcristallisée améliore la stabilité de la composition, améliorant ainsi les formes solides de posologie, comme les comprimés, les capsules, les suppositoires et les granules.

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