Stabilized, sterilized collagen scaffolds with active...

A - Human Necessities – 61 – L

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A61L 2/00 (2006.01) A61F 13/00 (2006.01) A61K 9/14 (2006.01) A61L 9/00 (2006.01) C12N 11/00 (2006.01) C12N 11/16 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2646067

Bioimplants and methods of making the bioimplants are provided. The bioimplants comprise biological tissues having conjugated thereto adjunct molecules. The biological tissues are sterilized with a chemical sterilizing agent, such as a water soluble carbodiimide. The processes of making the bioimplants include a process in which an adjunct molecule is conjugated to a biological tissue during the sterilization process.

La présente invention concerne des bioimplants et des procédés de fabrication desdits bioimplants. Les bioimplants contiennent des tissus biologiques comportant des molécules auxiliaires conjuguées. Les tissus biologiques sont stérilisés à l'aide d'un agent de stérilisation chimique, tel qu'un carbodiimide hydrosoluble. Les procédés de fabrication des bioimplants incluent un procédé permettant de conjuguer une molécule auxiliaire à un tissu biologique pendant le processus de stérilisation.

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