Stabilized steroid compositions

Details Stabilized steroid compositions Stabilized steroid compositions

A - Human Necessities

61

K

A61K 31/57 (2006.01) A61K 31/58 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2223385

The degradation of triamcinolone acetonide in aqueous solutions is studied under accelerated storage conditions of 70 ~C over the pH range 1-10. Trace level metal ions can markedly accelerate the oxidative degradation in neutral and basic solutions, but pH conditions and/or the inclusion of metal- sequestering agents, such as ethylenediamine tetra acetate (EDTA), in a preparation depresses the metal catalysis.

Il ressort de l'étude de la dégradation du triamcinolone acétonide en solution aqueuse, dans des conditions de stockage accéléré de 70 ·C au-dessus de la plage de pH 1-10, que des ions métalliques à l'état de trace peuvent accélérer notablement la dégradation oxydative dans des solutions neutres et basiques, mais les conditions de pH et/ou l'inclusion d'agents de séquestration de métaux tels que l'éthylènediamine-tétracétate (EDTA) dans une préparation réduit la catalyse du métal.

Affiliated with

Also associated with

Rating

Stabilized steroid compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stabilized steroid compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stabilized steroid compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1874294