Stabilized thrombin compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/08 (2006.01) A61K 9/19 (2006.01) A61K 38/55 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2687968

Stabilized thrombin compositions, processes for preparing them, and kits comprising them are disclosed. The compositions comprise thrombin, a bacteriostatically effective amount of benzyl alcohol or chlorobutanol, and 0.10% - 5.0% (w/v) sucrose in aqueous solution. The compositions are stable when stored at 2°C - 8°C for four weeks or more.

L'invention concerne des compositions de thrombine stabilisées, des procédés pour les préparer, et des kits les comprenant. Les compositions comprennent de la thrombine, une quantité bactériostatiquement efficace d'alcool benzylique ou de chlorobutanol, et 0,10 % à 5,0 % (poids/volume) de sucrose dans une solution aqueuse. Les compositions sont stables une fois stockées de 2°C à 8°C pendant quatre semaines ou plus.

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